| State: | NE |
| Type: | NE |
| Route: | 112 |
| Map: | Nebraska Highway 112 map.png |
| Map Notes: | Nebraska Highway 112 highlighted in red |
| Length Mi: | 15.69 |
| Length Round: | 2 |
| Length Ref: | [1] |
| Established: | 1939[2] |
| Direction A: | West |
| Terminus A: | southwest of Odell |
| Direction B: | East |
| Terminus B: | west of Blue Springs |
| Counties: | Gage |
| Previous Type: | NE |
| Previous Route: | 110 |
| Next Type: | NE |
| Next Route: | 116 |
Nebraska Highway 112 is a highway in southeastern Nebraska. Its western terminus is at the Kansas border where it continues as K-148 southwest of Odell. Its eastern terminus is at U.S. Highway 77 west of Blue Springs.
Nebraska Highway 112 begins at the border with Kansas, where it meets K-148. The highway heads north through farmland where it meets NE 8. It runs concurrently with NE 8 heading eastward through Odell. A few miles outside of Odell, the highway turns to the north again. It then continues northward until it terminates at US 77 west of Wymore.[1]