| Zipporah Sein | |
| Order: | Vice-President of the Karen National Union |
| Term Start: | December 2012 [1] |
| Term End: | April 2017 |
| Predecessor: | David Tharkabaw |
| Successor: | Saw Kwe Htoo Win |
| Order2: | General Secretary of the Karen National Union |
| Term Start2: | October 2008 |
| Term End2: | December 2012 |
| Predecessor2: | Padoh Mahn Sha Lah Phan |
| Successor2: | Saw Kwe Htoo Win |
| Birth Place: | Karen State, Burma |
| Death Place: | Mae Sariang, Thailand |
| Nationality: | Karen |
| Occupation: | Politician |
| Party: | Karen National Union |
| Parents: | Tamla Baw |
| Native Name Lang: | my |
Naw Zipporah Sein (Burmese: နော်စီဖိုးရာစိန် 1955 – 24 July 2024) was a Burmese Karen political activist who served as Vice-President of the Karen National Union.
Zipporah Sein was born in 1955 in Kayin State, Burma, and trained as a teacher before fleeing to Thailand in 1995. From 1998 to 2008, she was the coordinator and executive secretary of the Karen Women's Organization, which describes its mission as helping Karen women refugees.[2] She has been called a "heroine" by the Political Heroes website.[3]
Sein died from ovarian cancer at her home in Mae Sariang on 24 July 2024, at the age of 69.[4]