| Official Name: | Natalyino |
| Native Name: | Натальино |
| Settlement Type: | Selo |
| Pushpin Map: | Russia Amur Oblast#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Name1: | Amur Oblast |
| Subdivision Name3: | Blagoveshchensky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +9:00 |
| Coordinates: | 50.6333°N 176°W[1] |
Natalyino (Russian: Натальино) is a rural locality (a selo) in Natalyinsky Selsoviet of Blagoveshchensky District, Amur Oblast, Russia. The population was 303 as of 2018.[2] There are 5 streets.
Natalyino is located on the right bank of the Zeya River, 91 km north of Blagoveshchensk (the district's administrative centre) by road. Svetilovka is the nearest rural locality.[3]