Narnavirus Explained

Narnavirus is a genus of positive-strand RNA viruses in the family Narnaviridae. Fungi serve as natural hosts. There are two species in this genus.[1] Member viruses have been shown to be required for sexual reproduction of Rhizopus microsporus.[2] Narnaviruses have a naked RNA genome without a virion and derive their name from this feature.[3]

Virology

Structure

Narnaviruses have no true virion. They do not have structural proteins or a capsid.[4]

Genome

Narnaviruses have nonsegmented, linear, positive-sense, single-stranded RNA genomes. The genome has one open reading frame which encodes the RNA-dependent RNA polymerase (RdRp). The genome is associated with the RdRp in the cytoplasm of the fungi host and forms a naked ribonucleoprotein complex.

Replication cycle

Viral replication is cytoplasmic. Replication follows the positive-strand RNA virus replication model. Positive-strand RNA virus transcription is the method of transcription. The virus exits the host cell by cell-to-cell movement. Fungi serve as the natural host. Transmission routes are parental and sexual.

Taxonomy

The genus has the following two species:[5]

External links

Notes and References

  1. Web site: Viral Zone. ExPASy. 15 June 2015.
  2. 2020 . Narnaviruses: Novel players in fungal–bacterial symbioses . Espino-Vázquez AN . Bermúdez-Barrientos JR . Cabrera-Rangel JF . Córdova-López G . Cardoso-Martínez F . Martínez-Vázquez A . Camarena-Pozos DA . Mondo SJ . Pawlowska TE . Abreu-Goodger C . Partida-Martínez LP. . The ISME Journal . 14 . 7 . 1743–1754 . 10.1038/s41396-020-0638-y. 32269378 . 7305303 .
  3. Web site: Narnaviridae - Positive Sense RNA Viruses - Positive Sense RNA Viruses (2011) - ICTV. 2021-06-15. talk.ictvonline.org.
  4. Book: Dolja. V. V.. ELS. Koonin. E. V.. 2012. 978-0-470-01617-6. Capsid-Less RNA Viruses. 10.1002/9780470015902.a0023269.
  5. Web site: Virus Taxonomy: 2020 Release . International Committee on Taxonomy of Viruses (ICTV) . March 2021 . 16 May 2021.