| Nagykanizsa District | |
| Native Name: | Nagykanizsai járás |
| Native Name Lang: | hu |
| Settlement Type: | Districts of Hungary |
| Image Blank Emblem: | HUN Nagykanizsa Címer.svg |
| Blank Emblem Type: | Coat of arms |
| Subdivision Type: | Country |
| Subdivision Type1: | County |
| Subdivision Name1: | Zala |
| Seat Type: | District seat |
| Seat: | Nagykanizsa |
| Area Total Km2: | 907.91 |
| Area Rank: | 2nd in Zala |
| Population As Of: | 2011 census |
| Population Total: | 78,252 |
| Population Rank: | 2nd in Zala |
| Population Density Km2: | 86 |
Nagykanizsa (Hungarian: Nagykanizsai járás) is a district in southern part of Zala County. Nagykanizsa is also the name of the town where the district seat is found. The district is located in the Western Transdanubia Statistical Region.
Nagykanizsa District borders with Zalaegerszeg District and Keszthely District to the north, Marcali District (Somogy County) to the east, Csurgó District (Somogy County) to the south, the Croatian county of Koprivnica-Križevci and Lenti District to the west. The number of the inhabited places in Nagykanizsa District is 49.
The district has 1 urban county, 1 town and 47 villages.(ordered by population, as of 1 January 2013)[1] The bolded municipalities are cities.