Na+-transporting two-sector ATPase explained
| sodium-transporting ATPase, rotational mechanism |
| Ec Number: | 3.6.3.15 |
| Go Code: | 0046962 |
In enzymology, a Na+-transporting two-sector ATPase is an enzyme that catalyzes the chemical reaction
ATP + H2O
ADP + phosphate
Thus, the two substrates of this enzyme are ATP and H2O, whereas its two products are ADP and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (Na+-transporting).
References
- Solioz M, Davies K . 1994 . Operon of vacuolar-type Na+-ATPase of Enterococcus hirae . J. Biol. Chem. . 269 . 9453 - 9 . 8144530 . 13 .
- Takase K, Kakinuma S, Yamato I, Konishi K, Igarashi K, Kakinuma Y . 1994 . Sequencing and characterization of the ntp gene cluster for vacuolar-type Na+-translocating ATPase of Enterococcus hirae . J. Biol. Chem. . 269 . 11037 - 44 . 8157629 . 15 .
- Rahlfs S, Muller V . 1997 . Sequence of subunit c of the Na(+)-translocating F1F0 ATPase of Acetobacterium woodii: proposal for determinants of Na+ specificity as revealed by sequence comparisons . FEBS Lett. . 404 . 269 - 71 . 9119076 . 10.1016/S0014-5793(97)00088-4 . 2-3 .
