NUDT9 explained

ADP-ribose pyrophosphatase, mitochondrial is an enzyme that in humans is encoded by the NUDT9 gene.^{[1] [2] [3]}

Further reading

• Lin S . Cloning, expression and characterisation of a human Nudix hydrolase specific for adenosine 5'-diphosphoribose (ADP-ribose) . Biochim. Biophys. Acta . 1594 . 1 . 127–35 . 2002 . 11825615 . 10.1016/S0167-4838(01)00296-5 . vanc. Gasmi L . Xie Y . 3 . Ying . K . Gu . S . Wang . Z . Jin . H . Chao . Y . Wu . C .
• Strausberg RL . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . vanc. Feingold EA . Grouse LH . 3 . Derge . JG . Klausner . RD . Collins . FS . Wagner . L . Shenmen . CM . Schuler . GD . 2002PNAS...9916899M . free .
• Zhang HT . Interaction of C17orf25 with ADP-ribose pyrophosphatase NUDT9 detected via yeast two-hybrid method . Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao . 35 . 8 . 747–51 . 2004 . 12897971 . vanc. Yan ZQ . Hu XB . 3 . .
• Shen BW, Perraud AL, Scharenberg A, Stoddard BL . The crystal structure and mutational analysis of human NUDT9 . J. Mol. Biol. . 332 . 2 . 385–98 . 2003 . 12948489 . 10.1016/S0022-2836(03)00954-9 .
• Clark HF . The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment . Genome Res. . 13 . 10 . 2265–70 . 2003 . 12975309 . 10.1101/gr.1293003 . 403697 . vanc. Gurney AL . Abaya E . 3 . Baker . K . Baldwin . D . Brush . J . Chen . J . Chow . B . Chui . C .
• Ota T . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . vanc. Suzuki Y . Nishikawa T . 3 . Otsuki . Tetsuji . Sugiyama . Tomoyasu . Irie . Ryotaro . Wakamatsu . Ai . Hayashi . Koji . Sato . Hiroyuki . free .
• Gerhard DS . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . vanc. Wagner L . Feingold EA . 3 . Shenmen . CM . Grouse . LH . Schuler . G . Klein . SL . Old . S . Rasooly . R .
• Otsuki T . Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries . DNA Res. . 12 . 2 . 117–26 . 2007 . 16303743 . 10.1093/dnares/12.2.117 . vanc. Ota T . Nishikawa T . 3 . Hayashi . K . Suzuki . Y . Yamamoto . J . Wakamatsu . A . Kimura . K . Sakamoto . K . free .
• Carloto A . The specific, submicromolar-Km ADP-ribose pyrophosphatase purified from human placenta is enzymically indistinguishable from recombinant NUDT9 protein, including a selectivity for Mn2+ as activating cation and increase in Km for ADP-ribose, both elicited by H2O2 . Biochim. Biophys. Acta . 1760 . 10 . 1545–51 . 2006 . 16860484 . 10.1016/j.bbagen.2006.06.003 . vanc. Costas MJ . Cameselle JC . 3 . McLennan . Alexander G. . Ribeiro . João Meireles .

Notes and References

1. Perraud AL, Fleig A, Dunn CA, Bagley LA, Launay P, Schmitz C, Stokes AJ, Zhu Q, Bessman MJ, Penner R, Kinet JP, Scharenberg AM . ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology . Nature . 411 . 6837 . 595–9 . May 2001 . 11385575 . 10.1038/35079100 . 2001Natur.411..595P . 4338852 .
2. Perraud AL, Shen B, Dunn CA, Rippe K, Smith MK, Bessman MJ, Stoddard BL, Scharenberg AM . NUDT9, a member of the Nudix hydrolase family, is an evolutionarily conserved mitochondrial ADP-ribose pyrophosphatase . J Biol Chem . 278 . 3 . 1794–801 . Jan 2003 . 12427752 . 10.1074/jbc.M205601200 . free .
3. Web site: Entrez Gene: NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9.