NUCKS1 explained

Nuclear ubiquitous casein and cyclin-dependent kinases substrate is a protein that in humans is encoded by the NUCKS1 gene.^{[1] [2]}

Further reading

• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 .
• Thompson HG, Harris JW, Wold BJ, etal . Identification and confirmation of a module of coexpressed genes. . Genome Res. . 12 . 10 . 1517–22 . 2003 . 12368243 . 10.1101/gr.418402 . 187523 .
• Grundt K, Skjeldal L, Anthonsen HW, etal . A putative DNA-binding domain in the NUCKS protein. . Arch. Biochem. Biophys. . 407 . 2 . 168–75 . 2002 . 12413487 . 10.1016/S0003-9861(02)00513-1 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Beausoleil SA, Jedrychowski M, Schwartz D, etal . Large-scale characterization of HeLa cell nuclear phosphoproteins. . Proc. Natl. Acad. Sci. U.S.A. . 101 . 33 . 12130–5 . 2004 . 15302935 . 10.1073/pnas.0404720101 . 514446 . 2004PNAS..10112130B . free .
• Ballif BA, Villén J, Beausoleil SA, etal . Phosphoproteomic analysis of the developing mouse brain. . Mol. Cell. Proteomics . 3 . 11 . 1093–101 . 2005 . 15345747 . 10.1074/mcp.M400085-MCP200 . free .
• Grundt K, Haga IV, Aleporou-Marinou V, etal . Characterisation of the NUCKS gene on human chromosome 1q32.1 and the presence of a homologous gene in different species. . Biochem. Biophys. Res. Commun. . 323 . 3 . 796–801 . 2004 . 15381070 . 10.1016/j.bbrc.2004.08.153 .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Gevaert K, Staes A, Van Damme J, etal . Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC. . Proteomics . 5 . 14 . 3589–99 . 2006 . 16097034 . 10.1002/pmic.200401217 . 895879 .
• Beausoleil SA, Villén J, Gerber SA, etal . A probability-based approach for high-throughput protein phosphorylation analysis and site localization. . Nat. Biotechnol. . 24 . 10 . 1285–92 . 2006 . 16964243 . 10.1038/nbt1240 . 14294292 .
• Olsen JV, Blagoev B, Gnad F, etal . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. . Cell . 127 . 3 . 635–48 . 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . 7827573 . free .
• Grundt K, Haga IV, Huitfeldt HS, Ostvold AC . Identification and characterization of two putative nuclear localization signals (NLS) in the DNA-binding protein NUCKS. . Biochim. Biophys. Acta . 1773 . 9 . 1398–406 . 2007 . 17604136 . 10.1016/j.bbamcr.2007.05.013 .

Notes and References

1. Ostvold AC, Norum JH, Mathiesen S, Wanvik B, Sefland I, Grundt K . Molecular cloning of a mammalian nuclear phosphoprotein NUCKS, which serves as a substrate for Cdk1 in vivo . Eur J Biochem . 268 . 8 . 2430–40 . Apr 2001 . 11298763 . 10.1046/j.1432-1327.2001.02120.x . free .
2. Web site: Entrez Gene: NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1.