Talaporfin Explained

Talaporfin (INN, also known as aspartyl chlorin, mono-L-aspartyl chlorin e6, NPe6, or LS11) is a chlorin based photosensitizer used in photodynamic therapy (PDT).

It absorbs red light at 664-667 nm normally provided by a laser tuned to this wavelength.^[1]

It was approved in Japan (in 2004) for PDT of lung cancer and marketed as Laserphyrin.^[2]

References

Extracorporeal Photo-Immunotherapy for Circulating Tumor Cells

Notes and References

1. Usuda J, Kato H, Okunaka T, Furukawa K, Tsutsui H, Yamada K, Suga Y, Honda H, Nagatsuka Y, Ohira T, Tsuboi M, Hirano T . Photodynamic therapy (PDT) for lung cancers . Journal of Thoracic Oncology. 1 . 5 . 489–93 . June 2006 . 17409904 . 10.1016/S1556-0864(15)31616-6 . 19722977 .
2. Usuda J, Kato H, Okunaka T, Furukawa K, Honda H, Suga Y, Hirata T, Ohira T, Tsuboi M, Hirano T . Photodynamic therapy using Laserphyrin for centrally located early stage lung cancer. . Journal of Clinical Oncology . June 2006 . 24 . 18 suppl . 7229 . 10.1200/jco.2006.24.18_suppl.7229 .