NOXA1 explained
NADPH oxidase activator 1 is an enzyme that in humans is encoded by the NOXA1 gene.[1] [2]
Further reading
- Opitz N, Drummond GR, Selemidis S, Meurer S, Schmidt HH . The 'A's and 'O's of NADPH oxidase regulation: a commentary on "Subcellular localization and function of alternatively spliced Noxo1 isoforms" . Free Radical Biology & Medicine . 42 . 2 . 175–9 . Jan 2007 . 17189823 . 10.1016/j.freeradbiomed.2006.11.003 .
- Kim JS, Diebold BA, Babior BM, Knaus UG, Bokoch GM . Regulation of Nox1 activity via protein kinase A-mediated phosphorylation of NoxA1 and 14-3-3 binding . The Journal of Biological Chemistry . 282 . 48 . 34787–800 . Nov 2007 . 17913709 . 10.1074/jbc.M704754200 . free .
- Valente AJ, El Jamali A, Epperson TK, Gamez MJ, Pearson DW, Clark RA . NOX1 NADPH oxidase regulation by the NOXA1 SH3 domain . Free Radical Biology & Medicine . 43 . 3 . 384–96 . Aug 2007 . 17602954 . 10.1016/j.freeradbiomed.2007.04.022 .
- Huda Zoghbi . Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY . A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration . Cell . 125 . 4 . 801–14 . May 2006 . 16713569 . 10.1016/j.cell.2006.03.032 . 13709685 . free .
- Takeya R, Ueno N, Kami K, Taura M, Kohjima M, Izaki T, Nunoi H, Sumimoto H . Novel human homologues of p47phox and p67phox participate in activation of superoxide-producing NADPH oxidases . The Journal of Biological Chemistry . 278 . 27 . 25234–46 . Jul 2003 . 12716910 . 10.1074/jbc.M212856200 . free .
- Geiszt M, Lekstrom K, Witta J, Leto TL . Proteins homologous to p47phox and p67phox support superoxide production by NAD(P)H oxidase 1 in colon epithelial cells . The Journal of Biological Chemistry . 278 . 22 . 20006–12 . May 2003 . 12657628 . 10.1074/jbc.M301289200 . free .
- Bánfi B, Clark RA, Steger K, Krause KH . Two novel proteins activate superoxide generation by the NADPH oxidase NOX1 . The Journal of Biological Chemistry . 278 . 6 . 3510–3 . Feb 2003 . 12473664 . 10.1074/jbc.C200613200 . free .
Notes and References
- Scanlan MJ, Chen YT, Williamson B, Gure AO, Stockert E, Gordan JD, Türeci O, Sahin U, Pfreundschuh M, Old LJ . Characterization of human colon cancer antigens recognized by autologous antibodies . International Journal of Cancer . 76 . 5 . 652–8 . May 1998 . 9610721 . 10.1002/(SICI)1097-0215(19980529)76:5<652::AID-IJC7>3.0.CO;2-P . free .
- Web site: Entrez Gene: NOXA1 NADPH oxidase activator 1.