NOTUM (gene) explained

Notum, palmitoleoyl-protein carboxylesterase is a protein that in humans is encoded by the NOTUM gene.^[1]

Further reading

• Torisu Y, Watanabe A, Nonaka A, Midorikawa Y, Makuuchi M, Shimamura T, Sugimura H, Niida A, Akiyama T, Iwanari H, Kodama T, Zeniya M, Aburatani H . Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by beta-catenin/TCF . Cancer Sci. . 99 . 6 . 1139–46 . June 2008 . 18429952 . 10.1111/j.1349-7006.2008.00814.x . 13526819 . free . 11158900 .
• Kakugawa S, Langton PF, Zebisch M, Howell S, Chang TH, Liu Y, Feizi T, Bineva G, O'Reilly N, Snijders AP, Jones EY, Vincent JP . Notum deacylates Wnt proteins to suppress signalling activity . Nature . 519 . 7542 . 187–192 . March 2015 . 25731175 . 4376489 . 10.1038/nature14259 . 2015Natur.519..187K .

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Palmitoleoyl-protein carboxylesterase NOTUM

Notes and References

1. Web site: Entrez Gene: Notum, palmitoleoyl-protein carboxylesterase. 2018-06-15.