NKX-homeodomain factor explained

NKX-homeodomain factors are a family of homeodomain transcription factors that are critical regulators of organ development.^[1]

Human genes that encode NKX-homeodomain factors include:

• NKX1-1, NKX1-2
• NKX2-1, NKX2-2, NKX2-4, NKX2-8
• NKX3-1, NKX3-2
• NKX6-1, NKX6-2, NKX6-3

Notes and References

1. Stanfel MN, Moses KA, Schwartz RJ, Zimmer WE . Regulation of organ development by the NKX-homeodomain factors: an NKX code . Cell. Mol. Biol. (Noisy-le-grand) . Suppl 51 . OL785–99 . 2005 . 16405855 .