Neurogenin-1 Explained

Neurogenin-1 is a protein that in humans is encoded by the NEUROG1 gene.^{[1] [2]}

Interactions

NEUROG1 has been shown to interact with CREB-binding protein^[3] and decapentaplegic homolog 1.^[3]

Further reading

• McCormick MB, Tamimi RM, Snider L, Asakura A, Bergstrom D, Tapscott SJ . NeuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family . Molecular and Cellular Biology . 16 . 10 . 5792–800 . Oct 1996 . 8816493 . 231580 . 10.1128/mcb.16.10.5792.
• Sun Y, Nadal-Vicens M, Misono S, Lin MZ, Zubiaga A, Hua X, Fan G, Greenberg ME . Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms . Cell . 104 . 3 . 365–76 . Feb 2001 . 11239394 . 10.1016/S0092-8674(01)00224-0 . 1534352 . free .
• Franklin A, Kao A, Tapscott S, Unis A . NeuroD homologue expression during cortical development in the human brain . Journal of Child Neurology . 16 . 11 . 849–53 . Nov 2001 . 11732772 . 10.1177/08830738010160111201 . 20069074 .
• Kim S, Ghil SH, Kim SS, Myeong HH, Lee YD, Suh-Kim H . Overexpression of neurogenin1 induces neurite outgrowth in F11 neuroblastoma cells . Experimental & Molecular Medicine . 34 . 6 . 469–75 . Dec 2002 . 12526089 . 10.1038/emm.2002.65 . free .
• Fanous AH, Chen X, Wang X, Amdur RL, O'Neill FA, Walsh D, Kendler KS . Association between the 5q31.1 gene neurogenin1 and schizophrenia . American Journal of Medical Genetics Part B . 144B . 2 . 207–14 . Mar 2007 . 17044100 . 10.1002/ajmg.b.30423 . 24638656 .
• Liscovitch N, Chechik G . Specialization of gene expression during mouse brain development . PLOS Computational Biology . 9 . 9 . e1003185 . 2013 . 24068900 . 10.1371/journal.pcbi.1003185 . 3777910. 2013PLSCB...9E3185L . free .

Notes and References

1. Tamimi RM, Steingrimsson E, Montgomery-Dyer K, Copeland NG, Jenkins NA, Tapscott SJ . NEUROD2 and NEUROD3 genes map to human chromosomes 17q12 and 5q23-q31 and mouse chromosomes 11 and 13, respectively . Genomics . 40 . 2 . 355–7 . Mar 1997 . 9119405 . 10.1006/geno.1996.4578 .
2. Web site: Entrez Gene: NEUROG1 neurogenin 1.
3. Sun Y, Nadal-Vicens M, Misono S, Lin MZ, Zubiaga A, Hua X, Fan G, Greenberg ME . Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms . Cell . 104 . 3 . 365–76 . Feb 2001 . 11239394 . 10.1016/S0092-8674(01)00224-0 . 1534352 . free .