NBUMP explained

NBUMP is a highly selective 5-HT1A receptor partial agonist (Ki = 0.1 nM; IA = 40%) with an arylpiperazine structure.[1] It is one of the highest affinity ligands for the 5-HT1A receptor known. It displays 460- and 260-fold selectivity for 5-HT1A over the α1-adrenergic and D2 receptors, respectively.

See also

Notes and References

  1. Book: Glennon RA . Strategies for the development of selective serotonergic agents. Bryan Roth . Roth BL . The Serotonin Receptors: From Molecular Pharmacology to Human Therapeutics (The Receptors) . Humana Press . Totowa, NJ . 2006 . 1-58829-568-0 . https://books.google.com/books?id=J6i6YpvCQfIC&q=NBUMP&pg=PA113 . 113 .

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