3-fumarylpyruvate hydrolase explained

3-Fumarylpyruvate hydrolase
Ec Number:	3.7.1.20

3-Fumarylpyruvate hydrolase (nagK (gene), naaD (gene)) is an enzyme with systematic name 3-fumarylpyruvate hydrolyase.^{[1] [2]} This enzyme catalyses the following chemical reaction

3-fumarylpyruvate + H₂O

\rightleftharpoons fumarate + pyruvate

The enzyme is involved in bacterial degradation of 5-substituted salicylates.

Notes and References

1. Zhou NY, Fuenmayor SL, Williams PA . nag genes of Ralstonia (formerly Pseudomonas) sp. strain U2 encoding enzymes for gentisate catabolism . Journal of Bacteriology . 183 . 2 . 700–8 . January 2001 . 11133965 . 94927 . 10.1128/JB.183.2.700-708.2001 .
2. Qu Y, Spain JC . Molecular and biochemical characterization of the 5-nitroanthranilic acid degradation pathway in Bradyrhizobium sp. strain JS329 . Journal of Bacteriology . 193 . 12 . 3057–63 . June 2011 . 21498645 . 3133195 . 10.1128/JB.01188-10 .