N8-acetylspermidine oxidase (propane-1,3-diamine-forming) explained

N^8-acetylspermidine oxidase (propane-1,3-diamine-forming)
Ec Number:	1.5.3.15

N⁸-acetylspermidine oxidase (propane-1,3-diamine-forming) is an enzyme with systematic name N⁸-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming).^[1] This enzyme catalyses the following chemical reaction

N⁸-acetylspermidine + O₂ + H₂O

\rightleftharpoons propane-1,3-diamine + 4-acetamidobutanal + H₂O₂

This enzyme is also active n N¹-acetylspermine, and it has weak activity on N¹,N¹²-diacetylspermine.

Notes and References

1. Shukla OP, Müller S, Walter RD . Polyamine oxidase from Acanthamoeba culbertsoni specific for N8-acetylspermidine . Molecular and Biochemical Parasitology . 51 . 1 . 91–8 . March 1992 . 1565141 . 10.1016/0166-6851(92)90204-w .