N-carbamoyl-L-amino-acid hydrolase explained

N-carbamoyl-L-amino-acid hydrolase
Ec Number:	3.5.1.87
Go Code:	0050538

In enzymology, a N-carbamoyl-L-amino-acid hydrolase is an enzyme that catalyzes the chemical reaction

N-carbamoyl-L-2-amino acid (a 2-ureido carboxylate) + H₂O

\rightleftharpoons L-2-amino acid + NH₃ + CO₂

Thus, the two substrates of this enzyme are N-carbamoyl-L-2-amino acid and H₂O, whereas its 3 products are L-2-amino acid, NH₃, and CO₂.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-carbamoyl-L-amino acid amidohydrolase.

References

• Ogawa J, Miyake H, Shimizu S . 1995 . Purification and characterization of N-carbamoyl-L-amino acid amidohydrolase with broad substrate specificity from Alcaligenes xylosoxidans . Appl. Microbiol. Biotechnol. . 43 . 1039 - 43 . 8590654 . 10.1007/BF00166922 . 6 .