N-acylglucosamine-6-phosphate 2-epimerase explained

N-acylglucosamine-6-phosphate 2-epimerase
Ec Number:5.1.3.9
Cas Number:37318-35-7
Go Code:0047465

In enzymology, a N-acylglucosamine-6-phosphate 2-epimerase is an enzyme that catalyzes the chemical reaction

N-acyl-D-glucosamine 6-phosphate

\rightleftharpoons

N-acyl-D-mannosamine 6-phosphate

Hence, this enzyme has one substrate, N-acyl-D-glucosamine 6-phosphate, and one product, N-acyl-D-mannosamine 6-phosphate.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is N-acyl-D-glucosamine-6-phosphate 2-epimerase. Other names in common use include acylglucosamine-6-phosphate 2-epimerase, and acylglucosamine phosphate 2-epimerase. This enzyme participates in aminosugars metabolism.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and .

References