N-acyl-D-aspartate deacylase explained

N-acyl-D-aspartate deacylase
Ec Number:	3.5.1.83
Cas Number:	9031-86-1
Go Code:	0047422

In enzymology, a N-acyl-D-aspartate deacylase is an enzyme that catalyzes the chemical reaction

N-acyl-D-aspartate + H₂O

\rightleftharpoons a carboxylate + D-aspartate

Thus, the two substrates of this enzyme are N-acyl-D-aspartate and H₂O, whereas its two products are carboxylate and D-aspartate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-acyl-D-aspartate amidohydrolase. It employs one cofactor, zinc.

References

• Moriguchi M, Sakai K, Katsuno Y, Maki T, Wakayama M . 1993 . Purification and characterization of novel N-acyl-D-aspartate amidohydrolase from Alcaligenes xylosoxydans subsp. xylosoxydans A-6 . Biosci. Biotechnol. Biochem. . 57 . 1145 - 8 . 7763985 . 10.1271/bbb.57.1145 . 7 .
• Sakai K, Moriguchi M . 1995 . Cloning, expression and nucleotide sequence of the N-acyl-D-aspartate amidohydrolase gene from Alcaligenes xylosoxydans subsp. xylosoxydans A-6 . J. Ferment. Bioeng. . 80 . 311 - 317 . 10.1016/0922-338X(95)94197-Y . 4 .