MiPT explained

Verifiedrevid:415855405
Iupac Name:N-[2-(1H-indol-3-yl)ethyl]-N-methylpropan-2-amine
Imagel:MIPT.svg
Widthl:140
Imager:Methylisopropyltryptamine.png
Widthr:140
Legal Au:Unscheduled
Legal Ca:Unscheduled
Legal De:NpSG
Legal Uk:Class A
Legal Us:Unscheduled
Cas Number:96096-52-5
Pubchem:29935323
Chemspiderid:21106353
Chembl:353728
Unii:JO3SCR302A
C:14
H:20
N:2
Smiles:CC(C)N(C)CCc1c[nH]c2ccccc12
Stdinchi:1S/C14H20N2/c1-11(2)16(3)9-8-12-10-15-14-7-5-4-6-13(12)14/h4-7,10-11,15H,8-9H2,1-3H3
Stdinchikey:KTQJVAJLJZIKKD-UHFFFAOYSA-N

N-methyl-N-isopropyltryptamine (MiPT) is a psychedelic tryptamine, closely related to DMT, DiPT and miprocin. It was first synthesized by David Repke in 1984[1] and was subsequently evaluated and described in Alexander Shulgin's 1997 book TiHKAL.

Chemistry

MiPT is the N-isopropyl analog of DMT and the N-methyl analog of DiPT.

MiPT base, unlike many other tryptamines in their freebase form, does not decompose rapidly in the presence of light or oxygen.

In August 2019, Chadeayne et al. solved the crystal structure of fumarate salt of MiPT.[2]

Dosage

Moderate effects have been reported at 10-25 mg ingested orally, with effects lasting 4–8 hours. One of the test subjects in TiHKAL reported moderate effects at 20 mg ingested intranasally.

Effects

In TiHKAL, the subjective experience is reported to be biased towards mental (psychedelic/entheogenic) effects, with mild perceptual (sensory/hallucinogenic) alterations relative to other tryptamines.[3] Subjects reported enhancement of the visual field (brightened and modulated color perception) but a lack of visual distortion typical of tryptamines such as psilocin. Enhancement of auditory perception was also noted. Documented physical effects include stimulation, dry mouth, and muscle tension.

Legality

In the United States, MiPT is unscheduled but purchase, sale, or possession for human consumption could be prosecuted under the Federal Analogue Act.[4] MiPT is specifically mentioned in the DEA Orange Book.[5]

Sweden's public health agency suggested classifying MiPT as a hazardous substance, on May 15, 2019.[6]

See also

External links

Notes and References

  1. Glennon RA, Jacyno JM, Young R, McKenney JD, Nelson D . Synthesis and evaluation of a novel series of N,N-dimethylisotryptamines . Journal of Medicinal Chemistry . 27 . 1 . 41–45 . January 1984 . 6581313 . 10.1021/jm00367a008 .
  2. Chadeayne AR, Pham DN, Golen JA, Manke DR . The fumarate salts of the N-isopropyl-N-methyl derivatives of DMT and psilocin . Acta Crystallographica. Section E, Crystallographic Communications . 75 . Pt 9 . 1316–1320 . September 2019 . 31523457 . 6727059 . 10.1107/S2056989019011253 . free .
  3. Web site: #47 MIPT . Shulgin A, Shulgin A . Transform Press . September 1997 . Isomer Design . 28 November 2023.
  4. Web site: 21 U.S. Code § 841 - Prohibited acts A . 2016-08-02 . LII / Legal Information Institute . cs2.
  5. Web site: Orange Book - List of Controlled Substances and Regulated Chemicals . live . https://web.archive.org/web/20230306093455/https://www.deadiversion.usdoj.gov/schedules/orangebook/orangebook.pdf . 6 March 2023 . Drug Enforcement Administration.
  6. Web site: Folkhälsomyndigheten föreslår att 20 ämnen klassas som narkotika eller hälsofarlig vara . Folkhälsomyndigheten . sv . 15 May 2019 .