N,N-Didesmethyltamoxifen Explained

N,N-Desmethyltamoxifen is a metabolite of tamoxifen, a selective estrogen receptor modulator (SERM).[1] It is formed from N-desmethyltamoxifen and is an intermediate in the conversion of tamoxifen and N-desmethyltamoxifen into norendoxifen (4-hydroxy-N,N-desmethyltamoxifen), an active metabolite of tamoxifen.

Notes and References

  1. Sanchez-Spitman AB, Swen JJ, Dezentje VO, Moes DJ, Gelderblom H, Guchelaar HJ . Clinical pharmacokinetics and pharmacogenetics of tamoxifen and endoxifen . Expert Review of Clinical Pharmacology . 12 . 6 . 523–536 . June 2019 . 31008668 . 10.1080/17512433.2019.1610390 . free .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "N,N-Didesmethyltamoxifen".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.