| Mykhaylo Ishchenko | |
| Birth Date: | 19 May 1950 |
| Birth Place: | Morozovsk, Russian SFSR, Soviet Union |
| Height: | 191cm |
| Position: | Goalkeeper |
| Clubs1: | Burevestnik Zaporizhzhia |
| Years2: | 1976–1986 |
| Clubs2: | CSKA Kyiv |
| Clubs3: | →SKA Lviv |
| Nationalyears1: | 1971–1986 |
| Nationalteam1: | Soviet Union |
| Nationalcaps1: | 167 |
| Nationalgoals1: | 1 |
Mykhaylo Oleksiyovich Ishchenko (Михайло Олексійович Іщенко, born 19 May 1950) is a retired Soviet handball goalkeeper who competed in the 1972, 1976 and 1980 Summer Olympics. He won a gold medal in 1976 and a silver in 1980 and placed fifth in 1972. He won another set of a gold and a silver medal at the world championships.