Mycobacterium indicus pranii explained

Mycobacterium indicus pranii (MIP),[1] earlier known as Mw, is a non-pathogenic mycobacterial species, which, based on its growth characteristics and metabolic properties,[2] [3] is validly classified as a member of the Mycobacterium avium complex. The novelty of this bacterium is due to its translational application as an immunotherapeutic. The genome of the organism has now been completely sequenced.

The origin of the proposed name is a combination of the site of isolation of the bacterial species from India (indicus), discovery by Pran Talwar (pranii) and characterization at the National Institute of Immunology, India[4] (pranii).

Notes and References

  1. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0006263 Mycobacterium indicus pranii
  2. Rahman SA, Singh Y, Kohli S, Ahmad J, Ehtesham NZ, Tyagi AK, Hasnain SE. 2014. Comparative analyses of nonpathogenic, opportunistic, and totally pathogenic mycobacteria reveal genomic and biochemical variabilities and highlight the survival attributes of Mycobacterium tuberculosis. mBio 5(6):e02020. doi:10.1128/mBio.02020-14
  3. Rahman SA, Singh Y, Kohli S, Ahmad J, Ehtesham NZ, Tyagi AK, Hasnain SE. 2015. '"Mycobacterium indicus pranii" Is a Strain of Mycobacterium intracellulare': “M. indicus pranii” Is a Distinct Strain, Not Derived from M. intracellulare, and Is an Organism at an Evolutionary Transition Point between a Fast Grower and Slow Grower. mBio vol. 6 no. 2 e00352-15. doi: 10.1128/mBio.00352-15
  4. Book: Gupta . KR . Gupta . Amit. July 6, 2006 . Concise Encyclopaedia of India, Volume 3 . Atlantic Publishers & Distributors . 917 . 9788126906390.