| Mutum River | |
| Pushpin Map: | Brazil |
| River System: | Araguari River |
| Source1 Location: | Amapá state |
| Mouth Location: | Araguari River |
| Mouth Coordinates: | 1.3178°N -51.9895°W |
| Subdivision Type1: | Country |
| Subdivision Name1: | Brazil |
The Mutum River (Portuguese: Rio Mutum) is a river of Amapá state in north-eastern Brazil. It is a left tributary of the Araguari River.
The river defines the northern boundary of the Amapá National Forest, a sustainable use conservation unit created in 1989.