| Official Name: | Musakhel |
| Pushpin Map: | Afghanistan |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location in Afghanistan |
| Pushpin Mapsize: | 300 |
| Subdivision Type: | Country |
| Subdivision Name: |  Afghanistan |
| Subdivision Type1: | Province |
| Subdivision Name1: | Khost Province |
| Subdivision Type2: | District |
| Subdivision Name2: | Musakhel District |
| Unit Pref: | Imperial |
| Population Blank1 Title: | Ethnicities |
| Population Blank2 Title: | Religions |
| Coordinates: | 33.5333°N 69.7333°W |
| Elevation M: | 1835 |
Musakhel[1] is a village and the center of Musakhel District, Khost Province, Afghanistan. It is located at 33.5333°N 69.7333°W at 1835 m altitude. The town is located within the heartland of the Ahmadzai tribe of Ghilji Pashtuns.[2]