| Muro Leccese | |
| Official Name: | Città di Muro Leccese |
| Pushpin Label Position: | left |
| Coordinates: | 40.1°N 38°W |
| Region: | Apulia |
| Province: | Lecce (LE) |
| Mayor Party: | Uniti x Muro |
| Mayor: | Antonio Lorenzo Donno |
| Area Total Km2: | 16 |
| Population Total: | 4948 |
| Population As Of: | 31 December 2016 |
| Population Demonym: | Muresi |
| Telephone: | 0836 |
| Elevation M: | 82 |
| Postalcode: | 73036 |
| Saint: | Saint Orontius of Lecce |
| Day: | 26 August |
| Area Code: | 0836 |
Muro Leccese is a town and comune of 4948 inhabitants (2016), in the province of Lecce, in the Apulia region of south-east Italy.