Mucinous nevus explained

Synonym:Nevus mucinosus
Specialty:Dermatology

Mucinous nevus is a rare cutaneous condition characterized by hamartoma that can be congenital or acquired.[1] Mucinous nevus presents as multiple skin-coloured or brown asymptomatic papules or plaques. Mucinous nevus is diagnosed based of histological features. Treatment is not needed.

Signs and symptoms

Mucinous nevus appears as several skin-coloured to brownish papules or plaques that are asymptomatic; the individual lesions merge and expand to form a unilateral or zosteriform feature that is verrucous or nevoid.[2] [3] It normally starts to develop in early adulthood or from birth.[4] The main location is the trunk, which includes the back.[2] [5]

Causes

There has been reports of familial mucinous nevus, however there have been no reports of genetic abnormalities.[5] [4]

Diagnosis

Histologically, diffuse band-like mucin deposits in the uppermost layer of the dermis are indicative of mucinous nevus.[6] Hyaluronic acid is assumed to be the component of mucin since it reacts positively with alcian blue at pH 2.5 but does not at pH 0.5.[7] [8]

Treatment

Mucinous nevi are benign and don't need to be treated other than for aesthetic reasons.[2] Carbon dioxide laser therapy, scalpel dermabrasion, and surgical excision are treatment options.[9]

See also

Further reading

Notes and References

  1. Book: Rapini, Ronald P. . Bolognia, Jean L. . Jorizzo, Joseph L. . Dermatology: 2-Volume Set . Mosby . St. Louis . 2007 . 978-1-4160-2999-1 .
  2. Cobos . Gabriela . Braunstein . Inbal . Abuabara . Katrina . Chu . Emily Y. . James . William . Mucinous Nevus: Report of a Case and Review of the Literature . JAMA Dermatology . 150 . 9 . 2014-09-01 . 2168-6068 . 10.1001/jamadermatol.2013.9451 . 1018. 25029469 .
  3. Tardío . Juan C. . Granados . Rosario . The cellular component of the mucinous nevus consists of CD34-positive fibroblasts . Journal of Cutaneous Pathology . Wiley . 37 . 9 . 2010-07-08 . 0303-6987 . 10.1111/j.1600-0560.2009.01426.x . 1019–1020. 19765172 .
  4. CHEN . CHIA-WEI . TSAI . TSEN-FANG . CHEN . YU-FU . HUNG . CHIH-MING . Familial Mucinous Nevus . Pediatric Dermatology . Wiley . 25 . 2 . 2008 . 0736-8046 . 10.1111/j.1525-1470.2008.00664.x . 288–289. 18429813 .
  5. Perez-Crespo . M . Lopez-Navarro . N . Betlloch . I . Herrera . E . Niveiro . M . Gallego . E . Acquired and familial mucinous nevus . International Journal of Dermatology . Wiley . 50 . 10 . 2011-09-25 . 0011-9059 . 10.1111/j.1365-4632.2010.04520.x . 1283–1285. 21950298 .
  6. Lee . Min Young . Byun . Ji Yeon . Choi . Hae Young . Choi . You Won . Mucinous Nevus . Annals of Dermatology . Korean Dermatological Association and The Korean Society for Investigative Dermatology . 30 . 4 . 2018 . 465–467 . 1013-9087 . 10.5021/ad.2018.30.4.465 . 30065589 . 6029955 .
  7. Lim . J-H. . Cho . S-H. . Kim . H-O. . Kim . C-W. . Park . Y-M. . Mucinous naevus with atypical features . British Journal of Dermatology . Oxford University Press (OUP) . 148 . 5 . 2003 . 0007-0963 . 10.1046/j.1365-2133.2003.05334.x . 1064–1066. 12786849 .
  8. BRAKMAN . M. . STARINK . TH.M. . TAFELKRUYER . J. . BOS . J.D. . Linear connective tissue naevus of the proteoglycan type ('naevus mucinosus') . British Journal of Dermatology . Oxford University Press (OUP) . 131 . 3 . 1994 . 0007-0963 . 10.1111/j.1365-2133.1994.tb08526.x . 368–370.
  9. Chi . Ching-Chi . Wang . Shu-Hui . Lin . Paul Y. . Combined epidermal-connective tissue nevus of proteoglycan (a type of mucinous nevus): a case report and literature review . Journal of Cutaneous Pathology . Wiley . 36 . 7 . 2009 . 0303-6987 . 10.1111/j.1600-0560.2008.01123.x . 808–811. 19519615 .

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