| Mouthiers-sur-Boëme | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Mouthiers-sur-Boême 16.svg |
| Arrondissement: | Angoulême |
| Canton: | Boëme-Échelle |
| Insee: | 16236 |
| Postal Code: | 16440 |
| Mayor: | Michel Carteret[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Grand Angoulême |
| Coordinates: | 45.5556°N 0.1242°W |
| Elevation M: | 81 |
| Elevation Min M: | 59 |
| Elevation Max M: | 153 |
| Area Km2: | 34.71 |
Mouthiers-sur-Boëme (in French pronounced as /mutje syʁ bɔɛm/, literally Mouthiers on Boëme) is a commune in the Charente department in southwestern France.