| Official Name: | Moulhoule مول هولة |
| Settlement Type: | Town |
| Pushpin Map: | Djibouti |
| Pushpin Label Position: | bottom |
| Pushpin Mapsize: | 250 |
| Pushpin Map Caption: | Location in Djibouti |
| Subdivision Type: | Country |
| Subdivision Type1: | Region |
| Subdivision Name: | Djibouti |
| Subdivision Name1: | Obock |
| Unit Pref: | Metric |
| Coordinates: | 12.5833°N 54°W |
| Elevation M: | 6 |
Moulhoule (Arabic: مول هولة) is a town in the northern Obock region of Djibouti. It is situated on the west coast of the Red Sea, at its southern entrance. It is located on the RN-15 National Highway, which connects it to Obock, located some 70km (40miles) to the south and is 15km (09miles) south of the border with Eritrea.
Moulhoule is located beside the Bab el Mandeb Strait in the north-east of the Republic of Djibouti, 325km (202miles) (by road) from Djibouti City. Nearby towns and villages include Khôr ‘Angar (27 km), Rahayta (22 km), Assab (95 km).
Moulhoule has a hot desert climate (Köppen climate classification BWh).