| Official Name: | Mouddo |
| Settlement Type: | Town |
| Pushpin Map: | Djibouti |
| Pushpin Label Position: | bottom |
| Pushpin Mapsize: | 250px |
| Pushpin Map Caption: | Location in Djibouti |
| Subdivision Type: | Country |
| Subdivision Type1: | Region |
| Subdivision Name: | Djibouti |
| Subdivision Name1: | Tadjoura |
| Coordinates: | 12.3°N 68°W |
| Elevation M: | 310 |
Mouddo (Arabic: مودو) is a town in the northern Tadjoura region of Djibouti. Mouddo is on the edge of depression Andabba of a flooded plain case (very rare) of rain. It is situated about 90 kilometres (56 miles) north of Tadjoura and 14 km (8 mi) east of the border with Ethiopia.
There was a single class school until late 1980. A second class and a dormitory were then built. The civil war of the 1990s led to the closure and the deterioration of the school, which was reopened ten years later. The school Mouddo hosts hundreds of students from the Andabba or Madgoul areas.
Mouddo has a hot desert climate (Köppen climate classification BWh). Mouddo is noted for its very high summer humidity despite being a desert town. This combination of the desert heat and high humidity makes the apparent temperatures seem even more extreme. The sky is usually clear and bright throughout the year.