| Motuma Mekassa | |
| Native Name: | ሞቱማ መቃሳ |
| Native Name Lang: | am |
| Office1: | Minister of Defense |
| Term Start1: | 19 April 2018 |
| Term End1: | 16 October 2018 |
| Predecessor1: | Siraj Fegessa |
| Successor1: | Aisha Mohammed Mussa |
| Office2: | Minister of Mines, Petroleum and Natural Gas |
| Term Start2: | October 2016 |
| Term End2: | April 2018 |
| Predecessor2: | Tolosa Shagi |
| Successor2: | Melese Alemu |
| Office3: | Minister of Water, Irrigation and Electricity |
| Term Start3: | October 2015 |
| Term End3: | October 2016 |
| Successor3: | Sileshi Bekele |
| Birth Date: | 30 July 1965 |
| Party: | Ethiopian People's Revolutionary Democratic Front |
| Otherparty: | Oromo Peoples' Democratic Organization |
Motuma Mekassa (am|ሞቱማ መቃሳ, motuma mek’asa; born 30 July 1965) is an Ethiopian politician. He was elected to parliament in 2010 and ha served as Minister of Water, Irrigation and Electric, and as Minister for mines, Petroleum and Natural Gas.[1] He was also Ethiopian Minister of Defense briefly in 2018.