Motile sperm domain containing 2 explained

Motile sperm domain containing 2 is a protein that in humans is encoded by the MOSPD2 gene.^[1] It is an endoplasmic reticulum–resident protein involved in membrane contact site formation.^[2] Its domain homologous to Major Sperm Protein (MSP domain) is very similar to VAPA/VAPB, so it has been described as the third human member of the VAP protein family.

Further reading

• Velez Edwards DR, Naj AC, Monda K, North KE, Neuhouser M, Magvanjav O, Kusimo I, Vitolins MZ, Manson JE, O'Sullivan MJ, Rampersaud E, Edwards TL . Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study . Human Genetics . 132 . 3 . 323–36 . March 2013 . 23192594 . 3704217 . 10.1007/s00439-012-1246-3 .

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Mouse Motile sperm domain-containing protein 2

Notes and References

1. Web site: Entrez Gene: Motile sperm domain containing 2 .
2. Di Mattia T, Wilhelm LP, Ikhlef S, Wendling C, Spehner D, Nominé Y, Giordano F, Mathelin C, Drin G, Tomasetto C, Alpy F . Identification of MOSPD2, a novel scaffold for endoplasmic reticulum membrane contact sites . EMBO Reports . 19 . 7 . e45453 . June 2018 . 29858488 . 6030701 . 10.15252/embr.201745453 .