| Office: | 5th Mayor of Holon |
| Term Start: | 1993 |
| Predecessor: | Moshe Rom |
| Birth Date: | 1947 |
| Birth Place: | Holon, Israel |
| Party: | Labor |
Moti Sasson (Hebrew: מוטי ששון) (born 1947 in Holon) was the 5th mayor of Holon, Israel. He is a graduate of the History of the Middle East, Arabic language and literature department of Tel Aviv University. He was deputy and acting mayor between 1984–1989. He has worked hard to generate an image of the city as a 'Kids city', establishing the Holon Children's Museum, and large gardens and play parks around the city. Under his leadership Holon has been awarded 5 gold stars by the Council for a beautiful Israel.