Rabbi Moses Samuel Zuckermandl, also Zuckermandel (24 April 1836, Uherský Brod, Moravia 27 January 1917, Breslau (now Wrocław), Silesia) was a Czech-German rabbi, Talmudist, and Jewish theologian.
Zuckermandl was a student of Samson Raphael Hirsch in Nikolsburg. He subsequently studied at the Jewish Theological Seminary of Breslau.
He became a rabbi in Pleschen (now Pleszew), Prussia, and was appointed lecturer of the Mora-Leipziger Foundation at Breslau, on 1 April 1898. His major literary efforts related to the Tosefta and included the first critical edition based on variant manuscripts, particularly the Erfurt manuscript.