| Monsempron-Libos | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Monsempron-Libos (Lot-et-Garonne).svg |
| Arrondissement: | Villeneuve-sur-Lot |
| Canton: | Le Fumélois |
| Insee: | 47179 |
| Postal Code: | 47500 |
| Mayor: | Jean-Jacques Brouillet[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Fumel Vallée du Lot |
| Coordinates: | 44.4828°N 0.9442°W |
| Elevation M: | 116 |
| Elevation Min M: | 59 |
| Elevation Max M: | 155 |
| Area Km2: | 9.05 |
Monsempron-Libos (in French pronounced as /mɔ̃sɑ̃pʁɔ̃ libɔs/; Occitan (post 1500);: Montsempronh e Libòs) is a commune in the Lot-et-Garonne department in south-western France. Monsempron-Libos station has rail connections to Périgueux and Agen.