Molybdenum cofactor sulfurtransferase explained
| Molybdenum cofactor sulfurtransferase |
| Ec Number: | 2.8.1.9 |
Molybdenum cofactor sulfurtransferase (molybdenum cofactor sulfurase, ABA3, MoCo sulfurase, MoCo sulfurtransferase) is an enzyme with systematic name L-cysteine:molybdenum cofactor sulfurtransferase.[1] [2] [3] This enzyme catalyses the following chemical reaction
molybdenum cofactor + L-cysteine + 2 H+
thio-molybdenum cofactor + L-
alanine + H
2O
This enzyme contains pyridoxal phosphate.
Notes and References
- Bittner F, Oreb M, Mendel RR . ABA3 is a molybdenum cofactor sulfurase required for activation of aldehyde oxidase and xanthine dehydrogenase in Arabidopsis thaliana . The Journal of Biological Chemistry . 276 . 44 . 40381–4 . November 2001 . 11553608 . 10.1074/jbc.c100472200 . free .
- Heidenreich T, Wollers S, Mendel RR, Bittner F . Characterization of the NifS-like domain of ABA3 from Arabidopsis thaliana provides insight into the mechanism of molybdenum cofactor sulfuration . The Journal of Biological Chemistry . 280 . 6 . 4213–8 . February 2005 . 15561708 . 10.1074/jbc.m411195200 . free .
- Wollers S, Heidenreich T, Zarepour M, Zachmann D, Kraft C, Zhao Y, Mendel RR, Bittner F . Binding of sulfurated molybdenum cofactor to the C-terminal domain of ABA3 from Arabidopsis thaliana provides insight into the mechanism of molybdenum cofactor sulfuration . The Journal of Biological Chemistry . 283 . 15 . 9642–50 . April 2008 . 18258600 . 10.1074/jbc.m708549200 . free .
