Molecular promiscuity explained
Molecular promiscuity indicates the ability of a molecule to bind to interact with one or more other classes and subtypes of molecules, in synergistic or antagonistic ways. These interactions may involve multiple paracrine, endocrine and autocrine features.[1] [2] [3]
Notes and References
- Clark . Adrian JL . Chan . Li F . Promiscuity among the MRAPs . Journal of Molecular Endocrinology . April 2017 . 58 . 3 . F1–F4 . 10.1530/JME-17-0002 . 28213370 . free .
- Barth . Kenneth . Attardo Genco . Caroline . Microbial Degradation of Cellular Kinases Impairs Innate Immune Signaling and Paracrine TNFα Responses . Scientific Reports . 2016 . 6 . 34656 . 10.1038/srep34656 . 27698456 . 5048168 . 2016NatSR...634656B . free .
- Xiaofeng . Dai . Zhifu . Mao . Songping . Xie . Hao . Zhang . Jie . Huang . The CXCL12/CXCR4 autocrine loop increases the metastatic potential of non-small cell lung cancer in vitro . Oncology Letters . January 2013 . 5 . 1 . 277–282 . 10.3892/ol.2012.960. 3525341 . 23255935 . free .