| Mohammad-Qoli Khan | |
| Office: | Governor of Erivan Province (Chokhur-e Sa'd) |
| Predecessor: | Kaykhosrow Khan Cherkes |
| Successor: | Najafqoli Khan Cherkes |
| Termstart: | 1654 |
| Termend: | 1656 |
| Allegiance: | Safavid Iran |
| Occupation: | Official |
Mohammad-Qoli Khan or Mohammad-Qoli Khan b. Laleh Beg (fl. 17th-century), was a Safavid official who served as the governor (beglarbeg) of the Erivan Province (also known as Chokhur-e Sa'd) in 1654–1656, succeeding the Circassian Kaykhosrow Khan Cherkes to this post. According to the modern historian Rudi Matthee, during the "scheming" of incumbent grand vizier Mohammad Beg (1654–1666), by which the latter managed to get rid of his adversaries, Mohammad-Qoli Khan was probably also one of those officials who lost their job.