| Honorific Prefix: | Timsar |
| Mohammad-Hossein Shaker | |
| Allegiance: | Iran |
| Branch: | Imperial Iranian Army Islamic Republic of Iran Army |
| Rank: | Major general |
| Commands: | Chief-of-Staff |
Mohammad-Hossein Shaker (fa|محمدحسین شاکر) is an Iranian retired military officer who served as the Chief-of-Staff of the Islamic Republic of Iran Army from July 1979 until September 1979.