| Mizque River | |
| Name Etymology: | Quechua |
| Subdivision Type1: | Country |
| Subdivision Name1: | Bolivia |
| Subdivision Type3: | Region |
| Subdivision Name3: | Cochabamba Department, Mizque Province, Campero Province |
| Mouth: | Río Grande |
| Tributaries Left: | Uyuchama, Julpe |
The Mizque River (Quechua misk'i sweet) is a river of Bolivia in the Cochabamba Department. It is a tributary of Río Grande.