Mitragyna diversifolia explained

Mitragyna diversifolia is a tree species in the family Rubiaceae and found in Asia. The Catalogue of Life lists no subspecies.

Description

Mitragyna diversifolia is a deciduous under-story tree, that reaches up to 15 m in height. The branches are angled and cylindrical. The leaves are ovate-oblong to elliptic-ovate, averaging 146 × 93 mm in size, obtuse apex to shortly acuminate. The yellow corolla has white lobes. The fruit in the form of a capsule of 3–4 mm.[1]

Distribution

It is distributed through the forests of China (Yunnan), Cambodia, Indonesia, Laos, Burma, the Philippines, Thailand and Vietnam.

Uses

The genus mitragyna has been used traditionally to alleviate symptoms of fever, coughing, diarrhea, muscular pain and deworming,[2] although antioxidant and antimicrobial properties have also been found.[3] Typically these are consumed as a whole leaf or powder form, although gel-capsules, containing powder, are also used. Mitragyna diversifolia has been shown to possess pharmacological antidiarrheal properties, as well as analgesic properties.[4]

Phytochemicals

Mitragyna diversifolia leaf contains the alkaloids 7-hydroxy-isopaynantheine, 3-dehydro-paynantheine, 3-isopaynantheine-N(4)- oxide, mitrafoline, mitradiversifoline, specionoxeine-N(4)-oxide, specionoxeine-N(4)-oxide.[5]

References

  1. http://www.efloras.org/florataxon.aspx?flora_id=2&taxon_id=250096510 Mitragyna diversifolia in Flora of China
  2. Gong . Fang . Gu . Hai-Peng . Xu . Qi-tai . Kang . Wen-yi . Genus Mitragyna: Ethnomedicinal uses and pharmacological studies . Phytopharmacology . 2012 . 3 . 2 . 263–272 . 17 June 2020.
  3. Parthasarathy . Suhanya . Bin Azizi . Juzaili . Ramanathan . Surash . Ismail . Sabariah . Sasidharan . Sreenivasan . Said . Moh Ikram Mohd. . Mansor . Sharif Mahsufi . Evaluation of Antioxidant and Antibacterial Activities of Aqueous, Methanolic and Alkaloid Extracts from Mitragyna Speciosa (Rubiaceae Family) Leaves . Molecules . 2009 . 14 . 10 . 3964–3974 . 6255380. 10.3390/molecules14103964. 19924042 . free .
  4. Jebunnessa . Uddin . Shaikh Bokhtear . Mahabub-Uz-Zaman . Mohammed . Akter . Rasheda . Ahmed . Nazim Uddin . Antidiarrheal activity of ethanolic bark extract of Mitragyna diversifolia . Bangladesh Journal of Pharmacology . 2009 . 4 . 2 . 144–146 . 10.3329/bjp.v4i2.2801. free .
  5. 8878704 . 2022 . Ahmad . I. . Prabowo . W. C. . Arifuddin . M. . Fadraersada . J. . Indriyanti . N. . Herman . H. . Purwoko . R. Y. . Nainu . F. . Rahmadi . A. . Paramita . S. . Kuncoro . H. . Mita . N. . Narsa . A. C. . Prasetya . F. . Ibrahim . A. . Rijai . L. . Alam . G. . Mun'Im . A. . Dej-Adisai . S. . Mitragyna Species as Pharmacological Agents: From Abuse to Promising Pharmaceutical Products . Life . 12 . 2 . 193 . 10.3390/life12020193 . 35207481 . 2022Life...12..193A . free .

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