Mitochondrial tRNA pseudouridine27/28 synthase explained

Mitochondrial tRNA pseudouridine^27/28 synthase
Ec Number:	5.4.99.44

Mitochondrial tRNA pseudouridine^27/28 synthase (Pus2, Pus2p, RNA:pseudouridine synthases 2) is an enzyme with systematic name mitochondrial tRNA-uridine^27/28 uracil mutase.^[1] This enzyme catalyses the following chemical reaction

mitochondrial tRNA uridine^27/28

\rightleftharpoons mitochondrial tRNA pseudouridine^27/28

The mitochondrial enzyme Pus2p is specific for position 27 or 28 in mitochondrial tRNA.

See also

• PUS1
• TRNA pseudouridine38/39 synthase

Notes and References

1. Behm-Ansmant I, Branlant C, Motorin Y . The Saccharomyces cerevisiae Pus2 protein encoded by YGL063w ORF is a mitochondrial tRNA:Psi27/28-synthase . RNA . 13 . 10 . 1641–7 . October 2007 . 17684231 . 1986808 . 10.1261/rna.605607 .