| State: | MO |
| Type: | MO |
| Route: | 98 |
| Map Custom: | yes |
| Map Notes: | Route 98 highlighted in red |
| Established: | 1922 |
| Length Mi: | 8.376 |
| Direction A: | West |
| Direction B: | East |
| Terminus B: | Overton |
| Previous Type: | MO |
| Previous Route: | 97 |
| Next Type: | MO |
| Next Route: | 99 |
Route 98 is a highway in Cooper County. It stretches for 9.5 miles through a mostly rural area of Missouri.
In the west, Route 98 begins at Business Loop Interstate 70/Route 87 in Booneville. It proceeds eastward, traversing a largely rural area. Upon reaching Orchard Drive, Route 98 turns due south, but soon resumes an eastward course as it passes near the Jesse Viertel Memorial Airport. The highway approaches I-70, which it generally parallels for its entire length. Route 98 reaches its closest proximity to I-70 when it meets a junction with Route 179. It turns northeast and loses its designation at a railroad crossing and transitions into Cumberland Church Road, south of the Missouri River.