| State: | MO |
| Type: | Route |
| Route: | 114 |
| Map Custom: | yes |
| Map Notes: | MO 114 highlighted in red |
| Length Mi: | 22.900 |
| Direction A: | West |
| Terminus A: | in Dexter |
| Junction: | near Morehouse |
| Direction B: | East |
| Terminus B: | in Sikeston |
| Previous Type: | MO |
| Previous Route: | 113 |
| Next Type: | MO |
| Next Route: | 115 |
Route 114 is a highway in southeastern Missouri. Its eastern terminus is at Business U.S. Route 60 west of Sikeston; its western terminus is at Route 25 in Dexter.