| State: | MO |
| Type: | MO |
| Route: | 10 |
| Maint: | MoDOT |
| Established: | 1922 |
| Length Mi: | 46 |
| Map Custom: | yes |
| Map Notes: | Route 10 in red Business route in blue |
| Direction A: | West |
| Terminus A: | in Excelsior Springs |
| Junction: | in Richmond |
| Direction B: | East |
| Terminus B: | south of Carrollton |
| Previous Type: | MO |
| Previous Route: | 9 |
| Next Type: | MO |
| Next Route: | 11 |
Route 10 is a highway in Clay, Ray, and Carroll counties in western Missouri, United States. Its eastern terminus is at the concurrency of US 24/US 65 in Carrollton. Its western terminus is at US 69 in Excelsior Springs. A business loop of Route 10 travels through Richmond.
The western terminus of Route 10 is at an interchange with US 69. Then, it goes through a stretch with lots of turns in downtown Excelsior Springs. Between downtown Excelsior Springs and Route 10 Business, it intersects with a few supplemental routes. Shortly after intersecting with Route 10 Business, it meets with Route 210, which is where Route 210 ends. It also begins to enter Richmond there. Then, it has an interchange with Route T, which, according to satellite imagery, used to be the old alignment of Route 210. Shortly after, it has another interchange with Route 13. Then, it has another intersection with Route 10 Business, and then it leaves Richmond. Then, it passes through Hardin and Norborne, with rural farmland in-between. Then, Route 10 enters the southern part of Carrolton and intersects with Route 65 Business. Shortly after that, the route ends at an interchange with US 65 and US 24.
From 1922 to 1926, US 24 east of Carrollton was marked as Route 10. Until improvements to US 69 were carried through in the 1960s, Route 10 traveled along the current Route H through Prathersville and Mosby into Liberty. In Liberty, Route 10 followed Liberty Drive along Glenaire into Pleasant Valley, where it followed the current US 69 west to North Brighton Avenue. At North Brighton, it turned south and onto Winn Road, crossing what is now Interstate 35 (I-35). It follows sections of road that no longer exist to connect to Winn Road, traveling south and into Avondale as Walker Road. There are signs in Avondale to this day marking it as "Highway 10". It then followed the current route of Route 210 and Armour Road into North Kansas City, turning southward at Burlington Road/Route 9 and crossing the Missouri River terminating at US 24/US 40 in downtown Kansas City.
| State: | MO |
| Type: | MO-Bus |
| Route: | 10 |
| Length Mi: | 5.41 |
| Location: | Richmond |
A five mile business route of MO 10 exists in Richmond. According to satellite imagery, Route 10 used to run on Route 10 Business.