| Date: | July 3, 2021 |
| Venue: | Hotel Guaraní Asunción |
| Entrants: | 22 |
| Placements: | 11 |
| Winner: | Jimena Sosa Colonias Unidas |
| Before: | 2019 |
| Next: | 2022 |
Miss Grand Paraguay 2021 was the 4th edition of the Miss Grand Paraguay pageant, held on July 3, 2021, at the Hotel Guaraní in Asunción.[1] [2] The contest featured twenty-two candidates, either chosen through regional pageants or through central casting, competed for the title, of whom the representative from Colonias Unidas, Jimena Sosa, was named the winner.[1] She then represented Paraguay in the Miss Grand International 2021 pageant in Thailand, but got a non-placement.[3]
| Final results | Contestant | |
|---|---|---|
| Miss Grand Paraguay 2021 |
| |
| 1st Runner-Up |
| |
| 2nd Runner-Up |
| |
| 3rd Runner-Up |
| |
| 4th Runner-Up |
| |
| Top 11 |
|
22 contestants competed for the title.[4]
| State | Contestans | |
|---|---|---|
| Areguá | Juliel Pöckel | |
| Arroyos y Esteros | Nayeli Riquelme | |
| Asunción | Bianca Ayala | |
| Canindeyú | Elena Toledo | |
| Capiatá | Lenny Rojas | |
| Colonias Unidas | Jimena Sosa | |
| Concepción | Angelica Peña Testa | |
| Coronel Oviedo | Dahiana Aquino | |
| Encarnación | Emma Báez | |
| General Artigas | Fátima Ruíz Díaz | |
| Hernandarias | Violeta Van Humbeck | |
| Itauguá | Nara Bardales | |
| Luque | Gina Antonella | |
| Mariano Roque Alonso | Elena Mora | |
| Minga Guazú | Adriana Marecos | |
| Paraguarí | Eliana Fernández | |
 PAR Communities in Spain | Elicena Andrada | |
| Pedro Juan Caballero | Lisa Morigano | |
| Presidente Franco | Lorena Rodríguez | |
| San Lorenzo | Cecilla Salinas | |
| San Pedro | Liz Valdovinos | |
| Villarrica | Karen Rodríguez |