| Date: | April 16, 1999 |
| Venue: | Teatro Nacional de la Casa de la Cultura, Quito, Pichincha, Ecuador |
| Entrants: | 19 |
| Winner: | Carolina Alfonso |
| Represented: | Pichincha |
| Returns: | Azuay, Bolívar, Cotopaxi, El Oro, Galápagos, Imbabura, Pastaza, Napo and Tungurahua |
| Broadcaster: | Gamavisión |
The Miss Ecuador 1999 was held on April 16, 1999. There were 19 candidates for the national title; at the end of the night Soraya Hogonaga from Pichincha crowned Carolina Alfonso from Pichincha as Miss Ecuador 1999. The Miss Ecuador competed at Miss Universe 1999.