| Winner: | Liliana Maritza Fernández González |
| Represented: | Salcedo |
| Date: | January 29, 1973 |
| Venue: | Auditorio del Bueno Café del Hotel Lina, Santo Domingo, Dominican Republic |
| Next Pageant: | Miss Universe 1973 |
| Broadcaster: | Color Vision |
| Entrants: | 28 |
Señorita República Dominicana 1973 was held on January 29, 1973. This is a national beauty pageant held in the Dominican Republic. There were 28 candidates who competed for the national crown. The winner represented the Dominican Republic at the Miss Universe 1973. The Virreina al Miss Mundo entered Miss World 1973. Only 27 provinces and 1 municipality entered. The top 10 contestants paraded in evening gowns and answered questions to select the top five, who then answered more questions.