| Misema River | |
| Pushpin Map: | Canada Ontario |
| Pushpin Map Caption: | Location of the mouth of the Misema River in Ontario |
| Subdivision Type1: | Country |
| Subdivision Name1: | Canada |
| Subdivision Type2: | Province |
| Subdivision Name2: | Ontario |
| Subdivision Type3: | Region |
| Subdivision Name3: | Northeastern Ontario |
| Subdivision Type4: | Districts |
| Source1: | Sullivan Lake |
| Source1 Location: | Ben Nevis Township, Cochrane District |
| Source1 Coordinates: | 48.2806°N -79.7008°W |
| Source1 Elevation: | 375m (1,230feet) |
| Mouth: | Blanche River |
| Mouth Location: | Marter Township, Timiskaming District |
| Mouth Coordinates: | 47.9008°N -79.8772°W |
| Mouth Elevation: | 183m (600feet) |
| River System: | Saint Lawrence River drainage basin |
| Tributaries Left: | Little Misema River |
The Misema River is a river in Timiskaming District and Cochrane District in Northeastern Ontario, Canada.[1] It is in the Saint Lawrence River drainage basin and is a left tributary of the Blanche River.
The river begins at Sullivan Lake in geographic Ben Nevis Township, Cochrane District.[2] It exits the lake at the northeast and travels counterclockwise around the Pushkin Hills, part of the Blake River Megacaldera Complex,[3] eventually heading south into Timiskaming District and Misema Lake, where it takes in the left tributary Little Misema River in geographic Katrine Township.[4] It heads south, passes under the former Ontario Northland Railway's Nipissing Central Railway branchline and Ontario Highway 66, flows west through South Grassy Lake, the south and west again over the Eighty Foot Falls, site of Canadian Hydro Developers' Misema Dam and 3.2 MW hydroelectric powerplant,[5] and reaches its mouth at the Blanche River in Marter Township on the border with Chamberlain to the west. The Blanche River flows via the Ottawa River to the Saint Lawrence River.