| Mirpur Mathelo | |
| Native Name: | |
| Settlement Type: | Tehsil |
| Blank Emblem Size: | 100px |
| Blank Emblem Type: | Logo |
| Mapsize: | 280px |
| Map Caption1: | Location within Pakistan |
| Subdivision Type: | Country |
| Subdivision Name: | Pakistan |
| Subdivision Type1: | Province |
| Subdivision Name1: | Sindh |
| Subdivision Type2: | District |
| Subdivision Name2: | Ghotki District |
| Population As Of: | 1998 |
| Blank Name Sec1: | Number of towns |
| Blank Info Sec1: | 1 |
| Blank Name Sec2: | Number of Union Councils |
| Blank Info Sec2: | 10 |
| Timezone1: | PST |
| Utc Offset1: | +5 |
Mirpur Mathelo Tehsil is an administrative subdivision (tehsil) of Ghotki District in the Sindh province of Pakistan. It is administratively subdivided into ten Union Councils, two of which form the capital Mirpur Mathelo. It is headquarters of Ghotki district. The historic Shadani Darbar is located in Mirpur Mathelo Taluka.[1]
Popular places in Mirpur Mathelo include the Saint's Tomb. There are many public and private schools and colleges. Govt High School Mirpur Mathelo is very famous and old. There is IT and vocational institute Siscom Technologies.